Therefore, tetracyclines are prosecutorial appointed interior with drug effective against the fungi Candida (eg, nistati-nom). Chance of pseudomembranous colitis associated with suppression of normal intestinal microflora Niemi (strong abdominal cramping, diarrhea, bloody stools). Macrolides - erythromycin, clarithromycin, and prosecutorial roksitromitsin (refers to azalides) act on the prosecutorial subunit ribosome and the translocation break - the final step of protein synthesis in the ribosome-max bacteria. pylori. Aminoglycosides act on the 30S ribosomal subunit. Chloramphenicol was appointed interior, and in severe cases, intravenously. Aminoglycosides are used mainly for severe infections caused by susceptible micro-organisms to aminoglycosides (Sepsis, peritonitis, urinary tract infections, pneumonia, wound and burn infection). Dysbacteriosis develops in antibiotic suppression of the normal micro-flora of the body. Distinguish 3 generations of aminoglycosides: I generation - streptomycin, kanami-ching, neomycin; II generation - the gentamicin tobramycin; Generation III - amikacin, netilmicin. Rifampicin is rapidly developing resistance of microorganisms. For the discovery streptomycin - the first antibiotic effective for tuberculosis, Waksman (USA) prosecutorial 1952 received the Nobel Prize. Enter drug intramuscularly or intravenously (slowly or drip). At the most sensitive microorganisms’ macrolides act tank prosecutorial Well into prosecutorial cells of the body infected by bacteria. Act on the gram-negative bacteria: E. Roksitromitsin and clarithromycin appointed interior, 2 times a day, azithromycin - 1 time per day. Through chi-toplazmaticheskuyu membrane of bacteria penetrate through oxygen-dependent Bronchiolitis Obliterans Organizing Pneumonia transport (and therefore ineffective against anaerobic bacteria). Kanamycin is used in the stability of Mycobacterium tuberculosis to streptomycin-Mycin. Contraindicated in newborns (can cause "gray syndrome" - vomiting, diarrhea, bloating, hypothermia, vascular collapse, irregular breathing, skin color pepelnosery; mortality - Gymnasium Chloramphenicol inhibits hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs, which are inactivated by these enzymes. Intramuscularly or intravenously drip. Polymyxins, including polymyxin B, can have it <rotoksicheskoe and nephrotoxicity. With infectious eye prosecutorial (conjunctivitis, keratitis, blepharitis), chloramphenicol is used as eye drops or ointment. Bactericidal action of aminoglycosides. Streptomycin - a broad spectrum antibiotic. Side effects of rifampicin: flu-like syndrome, disorders of the function of liver and kidney, ataxia, blurred vision, disturbances menstrual cycle, skin reactions, red-brown staining of the lacrimal fluid, sweat, urine. Aminoglycosides - broad-spectrum antibiotics. Therefore, at start-Xia diarrhea receiving the drug should be discontinued. For example, prosecutorial suppressing the normal gut can cause intestinal candidiasis.
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